Vaccine Safety Forum: Summaries of Two Workshops by Vaccine Safety Forum

Author:Vaccine Safety Forum
Language: eng
Format: epub
Tags: Health and Medicine : Public Policy
Publisher: NATIONAL ACADEMY PRESS
Published: 1997-07-10T00:00:00+00:00

Introduction

As discussed at the workshop, a number of immunologic and genetic variables are likely to foster diverse responses to vaccines. Because vaccines work through their effects on the human immune system, some scientists who study vaccine adverse effects have concentrated on allergic reactions or autoimmune processes as potential causes of adverse effects. Reflecting these ideas, the first session of the workshop addressed research on immune responses to vaccine antigens. If adverse reactions to vaccines are autoimmune reactions, as discussed in the previous section, then susceptibility to adverse events after vaccination might depend in part on an inherited or genetic susceptibility to such reactions. If so, the study of such disorders might provide insight into genetic susceptibility and expression. Reflecting these issues, the second session of the workshop addressed genetic variability in immune factors, and the interaction of these factors with environmental agents.

Certain populations may be more susceptible to adverse events following vaccination because of some of these variables. The third section of the report discussed a selected number of these populations. The final section presents a preliminary research agenda of possible or putative links in these areas.

Download

Copyright Disclaimer:
This site does not store any files on its server. We only index and link to content provided by other sites. Please contact the content providers to delete copyright contents if any and email us, we'll remove relevant links or contents immediately.